Post-Doctoral Research Visit F/M Postdoc "Investigation of potential biomarkers to detect chronic inflammation in Multiple Sclerosis through diffusion MRI"

Contract type : Fixed-term contract

Level of qualifications required : PhD or equivalent

Fonction : Post-Doctoral Research Visit

Level of experience : Recently graduated

About the research centre or Inria department

The Inria Saclay-Île-de-France Research Centre was established in 2008. It has developed as part of the Saclay site in partnership with Paris-Saclay University and with the Institut Polytechnique de Paris .

The centre has 39 project teams , 27 of which operate jointly with Paris-Saclay University and the Institut Polytechnique de Paris; Its activities occupy over 600 people, scientists and research and innovation support staff, including 44 different nationalities.


This is a collaborative research project involving 2 partners.

Jing-Rebecca Li, Researcher (Applied Mathematics); Inria-Saclay, Équipe Idefix (Medical Imaging, Applied Mathematics); ENSTA Paris, Unité de Mathématiques Appliquées (UMA).  Institut Polytechnique de Paris.

Anne Kerbrat, Medical Doctor (Neurologist) and Emmanuel Caruyer, Researcher (Medical Imaging);  CHU de Rennes, Service de neurologie; Equipe Empenn, Univ Rennes, CNRS, Inria, Inserm, IRISA UMR 6074.

The postdoc will be based at Inria-Saclay, with regular visits to Rennes. 



Participation in the "Investigation of potential biomarkers to detect chronic inflammation in Multiple Sclerosis through diffusion MRI", a project funded within the Biomedical Engineering Seed Grant Program by the Fondation Bettencourt Schueller.


Main activities

Construction of a large data set of human brain cells simulation meshes.

Construction of a database of synthetic voxels and their diffusion MRI signals.

Design and optimization of new diffusion MRI sequences for microglia activation measurement.

Participation in image acquisition. 

Image and data analysis.

Writing and submission of scientific articles.  Publication of software and code for the numerical simulations on GitHub.  Publication of the synthetic data sets. 


Recent PhD in Applied Mathematics or Biomedical Engineering;

Programming skills in Matlab and Python;

Familarity with diffusion MRI and image analysis;

Knowledge of partial differential equations and numerical linear algebra;

Benefits package

  • Subsidized meals
  • Partial reimbursement of public transport costs
  • Leave: 7 weeks of annual leave + 10 extra days off due to RTT (statutory reduction in working hours) + possibility of exceptional leave (sick children, moving home, etc.)
  • Possibility of teleworking (after 6 months of employment) and flexible organization of working hours
  • Professional equipment available (videoconferencing, loan of computer equipment, etc.)
  • Social, cultural and sports events and activities
  • Access to vocational training
  • Social security coverage


Monthly gross salary : 2.788 euros